Increased BMI and IBD have causal effects on the risk of hidradenitis suppurativa, as shown by Mendelian randomization analysis. Moderate genetic correlations were found between HS and BMI, smoking, ...

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The schematic illustrates the comprehensive pipeline for Mendelian randomization analysis, starting with multi-omics data inputs from GWAS, eQTL, and pQTL studies, sourced from major databases such as ...

In Mendelian inheritance patterns, you receive one version of a gene, called an allele, from each parent. These alleles can be dominant or recessive. Non-Mendelian genetics don’t completely follow ...

Background: Observational studies have indicated a potential association between ankylosing spondylitis and elevated cardiovascular disease (CVD) risk. However, it remains uncertain whether this ...

A new study identifying 56 non-clinical risk factors associated with sudden cardiac arrest (SCA), spanning lifestyle, physical measures, psychosocial factors, socioeconomic status, and the local ...

Antonia Haynes is a Game Rant writer who resides in a small seaside town in England where she has lived her whole life. Beginning her video game writing career in 2014, and having an avid love of ...

Robbie has been an avid gamer for well over 20 years. During that time, he's watched countless franchises rise and fall. He's a big RPG fan but dabbles in a little bit of everything. Writing about ...

Real estate investor Mendel Steiner of Brooklyn’s Borough Park died on Thursday at 33 years old. Steiner, in his brief real estate career, acquired multifamily buildings across Chicago, Cleveland, ...

Although Mendelian randomization techniques can involve fairly computationally intensive analyses, the fundamental principles that guide these study designs are straightforward and if understood ...

It has been argued that survival bias may distort results in Mendelian randomization studies in older populations. Through simulations of a simple causal structure we investigate the degree to which ...