One of a ‘Kine’: Synthekine Engineers Cytokine Therapeutics to Treat Cancer and Inflammatory Disease
Cytokines are small proteins that enable cells to communicate with each other, particularly to modulate the immune system—an increasingly popular target in drug development for immunology, virology, ...
Cancer immunotherapy has advanced significantly in recent years, dramatically improving patient prognosis and survival. The majority of cancer immunotherapy research currently focuses on the first T ...
Cytokines are secreted proteins critical for immune regulation, cell signaling, and tissue homeostasis. These cells are increasingly recognized as key tools in biomedical research, particularly in ...
Structural equivalence is demonstrated through the comparison of a synthetic multinuclear metal complex (left) versus the designer enzyme in this report (right). A collaborative research team led by ...
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Human cytokine equipped with abiotic multinuclear metal center exhibits intrinsic and extrinsic functions
A collaborative research team has successfully developed designer enzymes that exhibit both intrinsic and extrinsic functions by transplanting a synthetic trinuclear zinc center into a human cytokine.
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