The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing the entire repair sequence as it unfolds. Instead of freezing cells at ...

Scientists at Utrecht University have developed a unique fluorescent sensor that lets us watch DNA damage and repair happen live inside living cells and organisms. Instead of relying on still ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature.

In the past few years, gel electrophoresis of DNA fragments has become an important complement to hybridization and amplification sequencing tools. As variations on PCR, RFLP, mutation sequencing, and ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

Research team led by Nagoya University develop a label-free method for detecting DNA amplification in real time based on refractive index changes in diffracted light. Polymerase chain reaction (PCR) ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University and colleagues have achieved a major breakthrough in understanding sperm DNA packaging. Using high-speed atomic force ...

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.