Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...

Figure 1: PDF specifically binds to the 50S ribosomal subunit via its C-terminal helix. On the basis of our biochemical results, we designed crystallographic experiments. We reasoned that structural ...

Ribosome biogenesis and translation are regulated at multiple levels and are associated with accurate cell growth and proliferation. The loss of key checkpoints during protein synthesis might ...

HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...

Why is ribosome display used? Ribosome display can be used to study the protein-protein interactions that occur during everyday metabolism. In addition, the technique allows scientists to identify the ...

Researchers have artificially engineered a complete ribosome—the cell-based machine that translates mRNA into proteins—in the laboratory. The ability to engineer the ribosome not only could help ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...

DNA gets all the glory, but genetic material wouldn’t be anywhere without ribosomes — cellular protein factories that build everything from insulin to fingernails. The Royal Swedish Academy of ...

Over the past decade or so, nanotechnology has produced small-molecule machines that can walk, perform basic chemical reactions, or do mechanical tricks, such as spin around or ratchet. Yet the field ...

Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...