Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

The fluorescence-imaging technology in cells allows study the cellular mechanisms of the organelles with multiple imaging approaches. Different fluorescent proteins work as protein tags in detecting ...

How many photons are in a Green Fluorescent Protein (GFP)? More than you may have thought. The illumination required to excite fluorophores leads to their gradual photodegradation, a phenomenon known ...

Researchers have reported a sample-prior-based approach to point spread function decoupling that improves system ...

A multimodal imaging study combines cryo-X-ray nanotomography and super-resolution fluorescence microscopy to reveal how protein-coated nanoparticles behave in cells. (Nanowerk Spotlight) The ...

Computational fluorescence microscopy (CFM) requires accurate point spread function (PSF) characterization for high-quality ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

A mechanosensitive fluorescent probe visualises and quantifies the mechanical stress on bacterial membranes upon contact with a surface. (Nanowerk News) In natural environments, bacteria rarely live ...

descSPIM enables three-dimensional imaging of diverse tissues like neural cells and cancerous tumors. The widespread dissemination and adoption of descSPIM can accelerate biomedical discoveries. Three ...