The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

UMass Chan Medical School scientists have nearly tripled the known number of potential regulatory elements in the genome to 2 ...

Chemical structure of guanine, showing its double-ring purine structure and the functional groups involved in hydrogen bonding with cytosine. (Image: Public Domain) Guanine has the chemical formula ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

Scientists at St. Jude Children’s Research Hospital found that tumor cells use LINE-1 retrotransposons to restructure the genome to promote cancer gene expression.

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed. The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a ...

The conservation of genome regulatory elements over long periods of evolution is not limited to vertebrates, as previously ...