Cancer researchers have long treated genetic chaos and epigenetic rewiring as separate engines of disease, two parallel ...

Cancer cells often use epigenetic changes to resist treatment, a major factor particularly in late-stage deaths from ovarian cancer. One potential epigenetic marker, DNA secondary structures known as ...

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression. In gynecological malignancies-including ovarian, cervical, and ...

Aging is the primary risk factor for numerous life-threatening diseases and has long been a central focus of biological research. Epigenetic reprogramming, a process that can modulate cell fate and ...

Scientists have discovered clues that may explain why some treatments stop working for people with bowel cancer—causing about 16,800 deaths in the U.K. every year. The study, led by researchers at The ...

This figure shows primary T cells modified using two approaches. CAR receptors are introduced through targeted DNA insertion (top), while CRISPRoff mRNA and guide RNAs silence additional genes through ...

Cancer remains a leading cause of global mortality, with therapeutic challenges primarily arising from drug resistance and limited treatment efficacy. Polypharmacology—the strategic use of ...

Great. Good morning, everyone. I'm Alexandra Byrne. I'm a reporter at GenomeWeb, and I will be your moderator for today's webinar. The title of today's webinar is beyond the genome: Measuring ...