The orchestration of T cell activation is central to immune defence and self-tolerance. Recent advances have revealed that T cells integrate signals from their antigen receptors alongside a network of ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

In living cells, regulation of the electrochemical environment is supposed to be managed by ion channels—protein complexes that reside in cell membranes and assume definite shapes. So, it’s surprising ...

“Expression tells us what cells do, but regulatory DNA tells us where they come from, how they develop, and which germ layer ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture. The cohesin complex dynamically restructures ...